Clinical Research Portfolio · 2026

Ruth
Lagarde

Clinical Operations & Patient Recruitment Strategy
Global CRO · Bilingual EN/FR · Phase II/III Trials

Patient Recruitment Enrollment Strategy Global CRO Sponsor Engagement Clinical Trial Diversity Bilingual EN/FR
About Ruth

Clinical Operations Professional

Syneos HealthSpecialist, R&R Ops Project Management · Remote
MS, Applied Clinical ResearchSt. Cloud State University · 2024 · 3.94 GPA
GCP CertifiedNIDA Clinical Trials Network / NIH · 2025
ACRAC CertifiedAdvanced Clinical Research Associate · CCRPS · 2025
PSM I · Scrum.orgProfessional Scrum Master · 2026
ICH GCP E6(R2)Harvard / Brigham & Women's Hospital · MRCT Center · 2021
Atlanta, GAOpen to global clinical trial operations roles
Professional Profile

Ruth Lagarde is a clinical trial operations professional with over five years of progressive experience leading global patient recruitment strategy and enrollment delivery across multi-phase studies at Syneos Health, one of the world's top-five contract research organisations.

Her work spans the full trial lifecycle, from study start-up and vendor onboarding through site activation, enrollment monitoring, and close-out. She currently manages a portfolio of concurrent Phase II and III studies across more than 25 global sites on five continents, overseeing multi-million dollar recruitment budgets, international vendor ecosystems, and cross-functional delivery teams spanning EU, North America, South America, Asia, and Africa.

Ruth brings particular depth in enrollment forecasting and real-time risk mitigation, building centralised tracking models that allow her teams to act before issues surface rather than after they appear in milestone reports. Her approach to site management is relationship-first: she trains and supports CRAs, engages sites as strategic partners, and builds the kind of sponsor confidence that comes from consistent, transparent delivery.

She is a dedicated advocate for clinical trial diversity and inclusive enrollment, designing recruitment strategies that reflect the epidemiology of each indication from protocol, not as a regulatory afterthought. This expertise is directly aligned with current FDA and ICH guidance on diverse representation in clinical research.

Ruth holds an MS in Applied Clinical Research with a medical device specialisation from St. Cloud State University, completed with a 3.94 GPA while simultaneously working in clinical operations at Syneos Health. She is bilingual in English and French, providing direct operational value across European site networks, multilingual regulatory submissions, and international sponsor communications.

"Clinical research moves fast. Getting the right patients into the right trials, on time, is how treatments become realities."
Current Role · Syneos Health

Global Portfolio Snapshot

Scope and scale of active clinical trial operations responsibilities

8+
Concurrent global clinical trials across multiple therapeutic areas
Ahead
Multiple studies enrolled ahead of projected timelines through data-driven forecasting
$20M+
Budget oversight across recruitment and operational activities
10+
Global vendor partners across recruitment, translation, digital, and eCOA
25+
Global sites across EU, NA, SA, Asia, and Africa
30+
CRAs trained and supported on recruitment strategy and site engagement
"Specialist in global patient recruitment strategy and clinical trial operations, with a consistent record of delivering enrollment on time and ahead of schedule across complex, multi-phase studies spanning five continents."
Clinical Experience

Therapeutic Area Portfolio

Phase II and Phase III trials (one global study, four North America)

Oncology

Breast Cancer · Solid Tumors

Phase II / III Global: EU · NA · SA · Asia · Africa
  • Led global patient recruitment and enrollment strategy across high-volume Phase III trials, serving as primary sponsor point of contact for enrollment delivery and performance oversight.
  • Developed and implemented a centralised enrollment tracking and forecasting model enabling real-time site performance monitoring and proactive risk mitigation across a global site network.
  • Designed a screening reservation system to control enrollment flow and prevent over-randomisation, ensuring data integrity and protocol compliance throughout the study lifecycle.
  • Managed a full vendor ecosystem including central recruitment campaigns, translation partners, and digital channels across EU, NA, SA, Asia, and Africa.
  • Directed global material development and translation workflows, coordinating proactive IRB, Ethics Committee, and Ministry of Health submissions across national and international studies.
  • Achieved enrollment targets ahead of projected schedule, contributing to accelerated study timelines and improved sponsor confidence in delivery capability.
  • Ensured inspection-ready TMF documentation through rigorous QC, version control, and reconciliation activities maintained throughout the study lifecycle.

Neurology / CNS

ADHD · Schizophrenia · Anxiety

Phase II / IIINorth America
  • Led recruitment strategy across complex CNS trials with high screen failure rates, developing targeted patient identification and engagement approaches.
  • Developed Patient Engagement Plans (PEP) and managed iterative updates throughout the study lifecycle to reflect evolving enrollment data and site performance.
  • Analysed full recruitment funnel data (referrals, screen failures, no-shows) to identify conversion bottlenecks and implement targeted optimisation strategies.
  • Partnered with CRAs and site teams through structured engagement plans, site-level coaching, and real-time performance feedback.
  • Managed central campaign performance across digital and traditional channels, adjusting tactics based on real-time enrollment data and site feedback.
  • Improved patient retention and protocol adherence through structured follow-up frameworks and proactive communication strategies.

Infectious Disease

COVID-19 · Influenza

Phase II / IIINorth America
  • Managed high-volume patient recruitment during compressed timelines requiring accelerated study start-up and enrollment ramp.
  • Ensured full regulatory compliance across IRB and Ethics Committee submissions under time-pressured conditions without sacrificing documentation quality.
  • Streamlined recruitment workflows and study start-up processes while maintaining GCP compliance and audit readiness throughout.
  • Monitored enrollment metrics daily, escalating risks and executing corrective actions in real time to maintain alignment with aggressive timelines.
  • Coordinated cross-functional teams across clinical operations, data management, and site networks to ensure timely milestone achievement.

Hematology

Sickle Cell Disease

Phase II / IIINorth America
  • Developed tailored recruitment strategy for a limited-eligibility rare disease population requiring creative patient identification and community outreach beyond standard channels.
  • Identified and resolved enrollment bottlenecks through targeted site outreach, feasibility reassessment, and adjusted tactics aligned to patient population epidemiology.
  • Collaborated with investigative sites, advocacy organisations, and community stakeholders to improve patient access and population-level study awareness.
  • Tracked site-level KPIs and enrollment data to identify underperforming sites early and implement support interventions.
  • Applied diversity-focused recruitment grounded in US epidemiological data, improving enrolled population representativeness and study validity.

Nephrology

Chronic Kidney Disease (CKD)

Phase II / IIINorth America
  • Supported clinical operations and patient recruitment execution across a multi-site North American study, coordinating site activities and campaign performance.
  • Ensured full TMF documentation compliance and regulatory standards were maintained with records audit-ready at all times.
  • Optimised screening and eligibility workflows to reduce patient drop-off at key conversion points, improving overall screen-to-enroll rates.
  • Maintained accurate enrollment tracking systems to provide reliable performance data for sponsor reporting and internal oversight.
  • Strengthened audit readiness through structured QC processes, documentation version control, and systematic reconciliation of study materials.
Technical Proficiency

Tools & Systems

Platforms and clinical research systems used across the portfolio

Clinical Data & EDC
Medidata Rave EDCTrialMaster EDCVeeva VaulteTMFCTMSIRT Systems
Analytics & Reporting
Power BISpotfireMS Excel (Advanced)Enrollment Dashboards
Productivity & Collaboration
MS Office SuiteMS TeamsGoogle WorkspaceSharePoint
Patient & Site Systems
eConsentIWRSeCOA / ePROElectronic DiariesWearables / Sensors
Regulatory & Documentation
GCP / ICH E6(R2)IRB SubmissionsEthics CommitteeTMF QCAudit Readiness
Medical Device Platform
Greenlight Guru ClinicalAE & Unscheduled EventsMedication Management
Partner Ecosystem

Vendor Network

Established working relationships across the full clinical recruitment vendor landscape

Central Recruitment Vendors
WePowerCVSAutoCruitment
Translation & Localisation
WelocalizeTransPerfect
IRT / IWRS Platforms
SuvodaEndpoint SystemsClarionAtreo
Patient Transport & Reimbursement
Scout Clinical

Get in Touch

Let's Work Together

Available for clinical trial operations, patient recruitment strategy, and global project management roles

ruth.lagarde@gmail.com LinkedIn Profile 470-586-8029

RUTH LAGARDE · CLINICAL RESEARCH PORTFOLIO · 2026 · CONFIDENTIAL